ChecklistGuro Drug Discovery and Development Lifecycle Management
Streamline your entire R&D pipeline with our end-to-end Drug Discovery and Development Lifecycle Management workflow. Optimize everything from target identification and lead optimization to clinical trial oversight and regulatory submission. Enhance data integrity, accelerate time-to-market, and ensure seamless cross-functional collaboration across the pharmaceutical value chain with precision-engineered process automation.
This Template was installed 2 times.
Start
Start of the Workflow/Process.
1. Register Lead Compound
Create a new entry in the 'Chemical Compounds' data model to initialize the discovery phase.
2. Fetch Target Protein Data
Retrieve existing biological target information from the 'Proteomics' data model.
3. In-Vitro Assay Execution
Assign a task to Lab Technicians to perform initial binding affinity tests.
4. Update Compound Potency Scores
Update the 'Potency' field in the 'Chemical Compounds' entry based on assay results.
5. Calculate IC50 Value
Execute a formula to calculate the half-maximal inhibitory concentration based on dose-response data.
6. Aggregate Toxicity Scores
Calculate the average toxicity score across all tested analogs in the current batch.
7. ADME Profiling Review
Create a task for Pharmacologists to review Absorption, Distribution, Metabolism, and Excretion data.
8. Generate Lead Candidate Profile
Create a new entry in the 'Lead Candidates' data model once a compound passes screening.
9. Notify Stakeholders of Hit Identification
Send an email to the Research Director when a significant hit is identified.
10. Pre-clinical Safety Assessment
Assign a task to the Toxicology team to initiate animal model studies.
11. Update Regulatory Status
Update the 'Regulatory Milestone' field in the 'Drug Program' data model.
12. Generate IND-Enabling Study Report
Create a comprehensive report summarizing all pre-clinical safety and efficacy data.
13. Urgent Safety Alert
Send an SMS to the Principal Investigator if unexpected toxicity is recorded in the data entry.
14. Remove Failed Analogs
Delete entries from the 'Active Screening' model for compounds that failed toxicity thresholds.
15. Retrieve Patent Information
Get intellectual property status from the 'IP & Patents' data model to ensure freedom to operate.
End
End of the Workflow/Process.
Start of the Workflow/Process.
Create a new entry in the 'Chemical Compounds' data model to initialize the discovery phase.
Retrieve existing biological target information from the 'Proteomics' data model.
Assign a task to Lab Technicians to perform initial binding affinity tests.
Update the 'Potency' field in the 'Chemical Compounds' entry based on assay results.
Execute a formula to calculate the half-maximal inhibitory concentration based on dose-response data.
Calculate the average toxicity score across all tested analogs in the current batch.
Create a task for Pharmacologists to review Absorption, Distribution, Metabolism, and Excretion data.
Create a new entry in the 'Lead Candidates' data model once a compound passes screening.
Send an email to the Research Director when a significant hit is identified.
Assign a task to the Toxicology team to initiate animal model studies.
Update the 'Regulatory Milestone' field in the 'Drug Program' data model.
Create a comprehensive report summarizing all pre-clinical safety and efficacy data.
Send an SMS to the Principal Investigator if unexpected toxicity is recorded in the data entry.
Delete entries from the 'Active Screening' model for compounds that failed toxicity thresholds.
Get intellectual property status from the 'IP & Patents' data model to ensure freedom to operate.
End of the Workflow/Process.
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