ChecklistGuro logo ChecklistGuro Solutions Industries Company Pricing

Pharmaceutical Packaging Integrity Checklist

Ensure product safety and regulatory compliance with our Pharmaceutical Packaging Integrity Checklist. This essential tool guides you through critical checks to verify package performance and protect your valuable medications. Maintain quality, minimize risk, and streamline your packaging validation process.

This Template was installed 2 times.

Primary Packaging Material Assessment

1 of 8

Evaluation of the container closure system's material properties and suitability for drug compatibility.

Material Specification Review Summary

Material Lot Status

Material Thickness (mm)

Density (g/cm³)

Material Certificate of Analysis (CoA)

Drug Compatibility Assessment Status

Observed Material Characteristics

Container Closure Sealing Integrity

2 of 8

Assessment of seal integrity, including visual inspection, leak testing (vacuum, pressure, dye penetration), and seal strength testing.

Vacuum Leak Test Pressure (inches of water)

Vacuum Leak Test Duration (seconds)

Leak Test Result

Leak Test Failure Description (if applicable)

Dye Penetration Test Performed?

Seal Image (if applicable)

Seal Strength (N)

Leak test performed date

Dimensional Accuracy & Tolerances

3 of 8

Verification that container dimensions and tolerances meet specifications to ensure proper dosing and functionality.

Container Height (mm)

Container Diameter/Width (mm)

Label Height (mm)

Label Width (mm)

Closure Height (mm)

Closure Diameter (mm)

Measurement Unit

Labeling & Identification

4 of 8

Confirmation that labeling is accurate, legible, and securely affixed, including lot numbers, expiry dates, and warnings.

Product Name

Batch Number

Manufacturing Date

Expiry Date

Label Orientation

Label Material

Label Image (for Reference)

Packaging Performance Testing

5 of 8

Evaluation of the packaged product’s resistance to various stresses (e.g., vibration, compression, temperature) mimicking distribution conditions.

Drop Height (cm)

Vibration Frequency (Hz)

Temperature (Celsius)

Humidity (%)

Observed Damage (if any)

Pass/Fail Result

Test Date

Test Data/Images

Tamper Evidence Evaluation

6 of 8

Assessment of tamper-evident features and their effectiveness in detecting unauthorized access.

Tamper-Evident Feature Type

Number of Tamper Indications Present

Indicator Integrity Status

Detailed Observation of Tamper Evidence

Supporting Photographs

Compliance with Specifications

Statistical Sampling Plan Verification

7 of 8

Confirmation that the sampling plan adheres to established statistical guidelines for accurate representation of the batch.

Sample Size (n)

Acceptance Quality Limit (AQL)

Sampling Method

Lot Size

Justification for Sampling Plan Selection

Criticality of Defect

Sampling Plan Review Date

Documentation Review

8 of 8

Verification of complete and accurate records related to packaging integrity assessments.

Document Review Date

Document Status (Reviewed/Approved/Rejected)

Review Comments/Observations

Supporting Documentation (e.g., Test Reports)

Reviewer Signature

Document Revision Number

We can do it Together

Need help with Checklists?

Have a question? We're here to help. Please submit your inquiry, and we'll respond promptly.

Email Address
How can we help?