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Pharmaceutical Quality Risk Management Checklist

Proactively identify and mitigate quality risks in pharmaceutical manufacturing. This checklist streamlines your risk assessment process, ensuring compliance and patient safety.

This Template was installed 1 times.

Risk Identification

1 of 9

Activities related to identifying potential hazards and risks within pharmaceutical processes.

Brief Description of Process/Activity

Potential Hazard/Risk Description

Process Steps Involved (Select All That Apply)

Regulatory/Guidance Relevance

Date of Initial Risk Identification

Identification Source (e.g., Audit Findings, Deviation Reports)

Risk Analysis - Severity Assessment

2 of 9

Evaluating the potential severity of impact if a risk were to occur.

Potential Impact on Patient Safety

Potential Impact on Product Quality

Estimated Number of Patients Potentially Affected

Description of Potential Adverse Effects

Impact on Regulatory Compliance

Estimated Financial Loss (if applicable)

Risk Analysis - Probability Assessment

3 of 9

Estimating the likelihood of a risk event occurring.

Probability Scale Value (1-5)

Justification for Probability Rating

Frequency of Occurrence

Factors Influencing Probability

Estimated Frequency (Events/Year)

Risk Evaluation - Prioritization

4 of 9

Ranking risks based on their combined severity and probability.

Severity Score

Probability Score

Risk Score (Severity x Probability)

Risk Priority Category

Justification for Prioritization

Risk Ownership Assigned

Risk Control Measures - Existing

5 of 9

Documentation of existing controls currently in place to mitigate identified risks.

Detailed Description of Existing Control

Control Type (e.g., Preventative, Detective, Corrective)

Frequency of Control Execution (e.g., daily, weekly, monthly)

Last Review/Verification Date of Control

Applicable Regulations/Guidelines Controlled By

Reviewer Signature

Risk Control Measures - Proposed

6 of 9

Planning and documenting proposed new or enhanced controls to address prioritized risks.

Detailed Description of Proposed Control

Estimated Cost of Implementation

Target Implementation Date

Responsible Department/Team

Control Type(s) (e.g., Administrative, Engineering, Procedural)

Supporting Documentation (e.g., SOP, Drawings)

Justification for Proposed Control

Risk Control Implementation

7 of 9

Tracking the implementation of proposed risk control measures and confirming their effectiveness.

Implementation Start Date

Planned Completion Date

Estimated Cost of Implementation

Description of Implementation Activities Performed

Implementation Status

Implemented By

Supporting Documentation (e.g., training records, SOP revisions)

Actual Cost of Implementation

Risk Review & Monitoring

8 of 9

Establishing procedures for regularly reviewing and monitoring the effectiveness of risk management processes and controls.

Last Review Date

Frequency of Review (in months)

Review Outcome (Satisfactory/Needs Improvement/Unsatisfactory)

Summary of Review Findings

Corrective Actions Identified (if any)

Target Completion Date for Corrective Actions

Reviewer Signature

Risk Status after Review (Increased/Decreased/No Change)

Documentation & Record Keeping

9 of 9

Ensuring complete and accurate records of the entire risk management process, including identification, analysis, evaluation, and controls.

Risk Assessment Review Date

Summary of Risk Assessment Findings

Supporting Documentation (e.g., protocols, reports)

Record Status (Active, Archived, Superseded)

Document Version Number

Reviewer Signature

Comments/Notes Regarding Documentation

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