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Pharmaceutical Transport Validation Checklist

Ensure secure and compliant drug transport! Our Pharmaceutical Transport Validation Checklist simplifies the validation process, minimizing risk and ensuring regulatory adherence. Perfect for temperature-sensitive pharmaceuticals.

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Initial Planning & Risk Assessment

1 of 8

Assessment of transport risks and development of validation plan.

Project Scope Definition

Product(s) Included in Validation

Number of Batches to be Validated

Planned Start Date of Validation

Potential Risks Associated with Transport

Transport Mode(s) Considered

Acceptance Criteria for Temperature Excursions (Celsius)

Packaging System Evaluation

2 of 8

Review of packaging materials and design for product protection.

Packaging Material Description

Package Weight (kg)

Primary Packaging Material

Secondary Packaging Material

Package Features

Packaging Material Certificate of Analysis

Rationale for Packaging Material Selection

Temperature Monitoring Equipment Qualification

3 of 8

Verification of data loggers and temperature sensors accuracy and reliability.

Data Logger Serial Number

Temperature Sensor Calibration Point 1 (°C)

Temperature Sensor Calibration Point 2 (°C)

Temperature Sensor Calibration Point 3 (°C)

Calibration Standard Used

Detailed Calibration Procedure

Calibration Completion Date

Calibration Start Time

Calibrator Signature

Simulated Transport Runs (Phase 1)

4 of 8

Controlled simulations of transport conditions to establish baseline performance.

Start Date of Simulation

Simulation Start Time

Ambient Temperature (°C)

Product Temperature (°C)

Origin Location

Destination Location

Transport Mode

Duration of Simulation (Hours)

Simulated Transport Runs (Phase 2) - Deviation Scenarios

5 of 8

Simulations incorporating potential deviations (e.g., delays, temperature excursions).

Deviation Type

Duration of Excursion (minutes)

Temperature Excursion Magnitude (°C)

Start Date of Delay

Start Time of Delay

Delay Duration (hours)

Description of Deviation

Location of Deviation Event

Data Analysis & Reporting

6 of 8

Review of temperature data and generation of validation report.

Minimum Acceptable Temperature (°C)

Maximum Acceptable Temperature (°C)

Number of Excursions

Summary of Temperature Excursions (if any)

Overall Validation Status

Date of Analysis Completion

Raw Data Files (CSV, Excel)

Analyst Signature

Corrective Actions & Verification

7 of 8

Implementation of corrective actions and verification of effectiveness.

Description of Corrective Action(s) Implemented

Quantity of affected product/materials

Date Corrective Action(s) Were Completed

Impact on Product Quality

Root Cause(s) Addressed

Signature of Responsible Person (Verification)

Periodic Review & Revalidation

8 of 8

Schedule for periodic review and revalidation of the transport validation.

Last Revalidation Date

Revalidation Cycle Frequency (in months)

Summary of Review Findings

Overall Validation Status

Justification for Validation Status (if not 'Valid')

Next Scheduled Revalidation Date

Reviewer Signature

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